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A O Shpakov Selected Research

Adenylyl Cyclases (Adenylyl Cyclase)

2/2016[THE CHANGES OF NOCICEPTIVE THRESHOLD AND ACTIVITY OF THE ADENYLYL CYCLASE SYSTEM IN THE SKELETAL MUSCLES OF RATS WITH ACUTE AND MILD TYPE 1 DIABETES MELLITUS ].
5/2015[BETA-ADRENERGIC REGULATION OF THE ADENYLYL CYCLASE SIGNALING SYSTEM IN MYOCARDIUM AND BRAIN OF RATS WITH OBESITY AND TYPES 2 DIABETES MELLITUS AND THE EFFECT OF LONG-TERM INTRANASAL INSULIN TREATMENT].
3/2015[Spatial memory and regulation of brain adenylyl cyclase by serotonin and dopamine in rat with streptozotocin diabetes].
1/2015[THE EFFECTS OF LONG-TERM METFORMIN TREATMENT ON THE ACTIVITY OF ADENYLYL CYCLASE SYSTEM AND NO-SYNTHASES IN THE BRAIN AND THE MYOCARDIUM OF RATS WITH OBESITY].
9/2014[Attenuation of inhibitory influence of hormones on adenylyl cyclase systems in the myocardium and brain of rats with obesity and type 2 diabetes mellitus and effect of intranasal insulin on it].
3/2014[A change of hormonal regulation of adenylyl cyclase in the epididymal adipose tissue of rats with experimental models of diabetes mellitus].
1/2014[The influence of two-month treatment with bromocryptine on activity of the adenylyl cyclase signaling system in the myocardium and testes of rats with type 2 diabetes mellitus].
1/2014[The functioning of hormone-sensitive adenylyl cyclase system in the peripheral tissiues in diabetes mellitus].
1/2014The influence of bromocryptine treatment on activity of the adenylyl cyclase system in the brain of rats with type 2 diabetes mellitus induced by high-fat diet.
3/2013[Effects of intranasal insulin and serotonin on functional activity of the adenylyl cyclase system in the myocardium, ovaries, and uterus of rats with prolonged neonatal model of diabetes mellitus].
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A O Shpakov Research Topics

Disease

21Type 2 Diabetes Mellitus (MODY)
02/2022 - 10/2008
21Diabetes Mellitus
05/2021 - 12/2006
18Insulin Resistance
01/2019 - 01/2012
9Type 1 Diabetes Mellitus (Autoimmune Diabetes)
07/2019 - 01/2010
9Hyperglycemia
01/2019 - 11/2007
8Obesity
01/2019 - 09/2014
7Experimental Diabetes Mellitus
11/2019 - 01/2005
6Metabolic Syndrome (Dysmetabolic Syndrome X)
11/2019 - 05/2015
5Body Weight (Weight, Body)
11/2017 - 01/2014
4Cognitive Dysfunction
11/2019 - 11/2015
4Glucose Intolerance
01/2019 - 01/2014
3Alzheimer Disease (Alzheimer's Disease)
01/2019 - 10/2015
3Starvation
07/2014 - 04/2007
2Hyperthyroidism
04/2022 - 03/2020
2Neoplasms (Cancer)
03/2020 - 01/2001
2Hyperinsulinism (Hyperinsulinemia)
01/2019 - 01/2014
2Dyslipidemias (Dyslipidemia)
01/2017 - 11/2015
2Autoimmune Diseases (Autoimmune Disease)
07/2016 - 01/2015
2Peripheral Nervous System Diseases (PNS Diseases)
02/2016 - 02/2013
2Ganglion Cysts (Ganglion)
04/2005 - 04/2005
1Hypothyroidism
04/2022
1Graves Disease (Basedow Disease)
03/2020
1Weight Loss (Weight Reduction)
11/2019
1Feeding and Eating Disorders (Eating Disorder)
11/2019
1Lactic Acidosis
01/2019
1Brain Ischemia (Cerebral Ischemia)
01/2019
1Ischemia
01/2019
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2019
1Genetic Predisposition to Disease (Genetic Predisposition)
11/2017
1Hyperhomocysteinemia
01/2017
1Stiff-Person Syndrome (Stiff Man Syndrome)
07/2016
1Encephalomyelitis (Myeloencephalitis)
07/2016
1Myasthenia Gravis
07/2016
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
07/2016

Drug/Important Bio-Agent (IBA)

31Insulin (Novolin)FDA Link
05/2020 - 04/2005
24Adenylyl Cyclases (Adenylyl Cyclase)IBA
02/2016 - 01/2005
12Streptozocin (Streptozotocin)FDA Link
02/2022 - 11/2007
11Glucose (Dextrose)FDA LinkGeneric
01/2020 - 11/2007
11Hormones (Hormone)IBA
09/2014 - 12/2006
8Metformin (Glucophage)FDA LinkGeneric
02/2022 - 01/2015
7Proteins (Proteins, Gene)FDA Link
09/2014 - 01/2001
6MelanocortinsIBA
01/2019 - 01/2016
6Serotonin (5 Hydroxytryptamine)IBA
01/2018 - 04/2005
6Peptides (Polypeptides)IBA
01/2017 - 04/2005
5Pharmaceutical PreparationsIBA
04/2022 - 01/2015
5CarbohydratesIBA
11/2019 - 01/2012
5C-PeptideIBA
07/2019 - 01/2013
5GTP-Binding Proteins (G-Protein)IBA
11/2007 - 01/2001
4Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
04/2022 - 11/2015
4RelaxinIBA
05/2020 - 04/2007
4EnzymesIBA
11/2015 - 01/2007
4Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
09/2014 - 11/2007
4Biogenic Amines (Biogenic Amine)IBA
01/2012 - 01/2005
3Thyrotropin Receptors (Thyrotropin Receptor)IBA
04/2022 - 03/2020
3Phosphotransferases (Kinase)IBA
05/2020 - 01/2016
3LeptinIBA
01/2019 - 01/2014
3Isoproterenol (Isoprenaline)FDA LinkGeneric
05/2015 - 04/2007
3Insulin-Like Growth Factor I (IGF-1)IBA
01/2014 - 04/2005
2Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
02/2022 - 11/2010
2LH Receptors (LH Receptor)IBA
02/2022 - 05/2021
2Glucagon-Like Peptide 1 (GLP 1)IBA
01/2019 - 01/2012
2Dopamine (Intropin)FDA LinkGeneric
01/2018 - 03/2015
2CholesterolIBA
06/2017 - 01/2015
2Triglycerides (Triacylglycerol)IBA
06/2017 - 01/2014
2Vasodilator Agents (Vasodilators)IBA
01/2017 - 11/2015
2Dopamine Receptors (Dopamine Receptor)IBA
01/2017 - 01/2014
2EpitopesIBA
07/2016 - 01/2015
2AntibodiesIBA
07/2016 - 01/2015
2Adrenergic Agents (Adrenergic Drugs)IBA
05/2015 - 01/2012
2Adrenergic Agonists (Adrenergic Receptor Agonist)IBA
05/2015 - 04/2005
2Melanocortin Receptors (Melanocortin Receptor)IBA
01/2015 - 01/2012
2ColforsinIBA
09/2014 - 11/2007
2Peptide Hormones (Polypeptide Hormones)IBA
11/2010 - 04/2007
2Heterotrimeric GTP-Binding Proteins (Heterotrimeric G-Proteins)IBA
11/2010 - 12/2006
2Guanosine Triphosphate (GTP)IBA
04/2007 - 01/2001
1GonadotropinsIBA
02/2022
1pyrimidineIBA
05/2021
1PyrimidinesIBA
05/2021
1pyridineIBA
05/2021
1AMP-Activated Protein KinasesIBA
05/2020
1GangliosidesIBA
01/2020
1Protein Tyrosine PhosphatasesIBA
01/2019
1Glucagon-Like Peptide-1 ReceptorIBA
01/2019
1Adenosine Triphosphatases (ATPase)IBA
01/2019
1Transaminases (Aminotransferases)IBA
01/2019
1Lactic Acid (Lactate)FDA LinkGeneric
01/2019
1GhrelinIBA
01/2019
1Vasoconstrictor AgentsIBA
01/2017
1Endothelin-1 (Endothelin 1)IBA
01/2017
1Mesylates (Mesylate)IBA
01/2017
1Nitric Oxide (Nitrogen Monoxide)FDA Link
01/2017
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
07/2016
1Glutamic Acid (Glutamate)FDA Link
07/2016
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
07/2016

Therapy/Procedure

6Therapeutics
07/2020 - 01/2012
3Intranasal Administration
01/2020 - 09/2011
1Oral Administration
01/2019
1Gastrectomy
01/2019
1Gastric Bypass (Roux-en-Y Gastric Bypass)
01/2019
1Bariatric Surgery
01/2019